The real trick to roulette is to get lucky, then quit while you're ahead. Every spin has a 1 in 37 (for European) or 1 in 38 (for American) chance of landing in a given pocket.
Some bets in American Roulette have an even higher house edge than the 5.26% average. For example, a bet on the Five Numbers (0, 00, 1, 2, 3) carries a house edge of 7.89%. Outside bets in roulette carry the lowest risk. They cover more numbers yet the payouts are lower (1/1 for Red, Black, Odd, Even, 1 18, 19 36).