Yes, Stake.us is legit, as it's affiliated with the well-known Stake brand of sportsbook and crypto casino. They ensure that your data is secure, and as they only use crypto as a payment method, you don't need to be concerned about giving out your bank card or account details.
Does Stake.us pay out? Yes and no. Stake.us doesn't pay out real money for wins on their site. They award Stake Cash, a type of virtual currency which you can collect and redeem for gift cards, cryptocurrency, and other rewards.