Yes and no. Stake.us doesn't pay out real money for wins on their site. They award Stake Cash, a type of virtual currency which you can collect and redeem for gift cards, cryptocurrency, and other rewards. The speed depends on your chosen casino banking option.
Stake.us is a social casino, where you can play with Gold Coins and Stake Cash (sweepstakes). Stake is a cryptocurrency gambling site where real money betting takes place. The latter is most definitely illegal in the United States, and you will be denied access if you try to enter it from any state.