If the tie is between two clubs, then the tie is broken using the head-to-head goal difference for those clubs (without away goals rule). If the tie is between more than two clubs, then the tie is broken using the games the clubs have played against each other: a) head-to-head points. b) head-to-head goal difference.
La Liga decides their tie-breakers between two level clubs first through goal difference, like in the Premier League. Then, if the clubs are still level, the ranking will be resolved with a tie-break match in a neutral stadium.